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62 year old male: Chest Discomfort – Conclusion

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This is the conclusion to our three part case series, 62 year old male: Chest Discomfort. Before reading the conclusion, we suggest you check out Part I and Part II. Thanks again to Vince DiGiulio, EMT-CC for this wonderful case!

When we last left off, our patient had experienced a resolution of his chest pain accompanied by changes on his 12-Lead ECG. The ED physician had called cardiology, but they were unimpressed. Are we comfortable with this?

Let's review our patients'  first 12-Lead.

Well Page Him Again - Initial 12-Lead

We have a narrow complex, regular rhythm at 90 bpm consistent with a normal sinus rhythm. Flat or downsloping ST segments are visible in leads III and aVF. Additionally, ST-Elevation is present in leads V1 through V4. As some readers pointed out, this is diagnostic for an Anterior Wall Myocardial Infarction. There are also some subtle hints that this is not a normal variant:

  • Dr. Smith included in the comments that the R-wave amplitude of V2-V4 is only 10 mm. In cases of AWMI, a loss of precordial R-wave amplitude is often noted.
  • If you compare the T-waves in V1 and V6, you'll note that they are much larger in V1 than in V6. Dr. Henry J. L. Marriott describes this finding as a "loss of precordial T-wave balance." Dr. Mattu covers this in depth in his excellent video New Tall T-Waves in V1.

The most important point is that there is no other explanation for our patient's ST-Elevation. There is no LVH or BBB present and Early Repolarization is a diagnosis of exclusion in a 62 year old patient.

Regardless, any patient with chest pain should be evaluated with serial ECG's. During our patient's second 12-Lead, he happened to be pain free:

Well Page Him Again - Repeat 12-Lead

Our repeat 12-Lead shows a normal sinus rhythm, with the development of terminal T-wave inversions in leads V1-V4. Several of our readers correctly pointed out that these are the hallmarks of the eponymous Wellens' Syndrome (or Wellens' Warning). Interestingly enough, the computer's interpretation now displays *** ACUTE MI ***.

Well Page Him Again - Wellens Syndrome

So what is the importance of this finding?

In 1982, Hein JJ Wellens identified two types of abnormal T-waves associated with critical, proximal LAD stenosis. The first type, not seen in our case, features deeply inverted, symmetric T-waves in the anterior precordial leads. The second type, featured above, are characterized by biphasic T-waves. In his seminal study, Wellens found that these electrocardiographic patterns were most often seen during pain free periods. Subsequent studies showed that nearly every patient with Wellens' Syndrome had blockage in the LAD, ranging from 50-100%!

So what happened with our patient?

Our patient continued to experience transient episodes of chest pain. His troponin-I levels returned at 1.09 ng/mL 20 minutes after the pain-free ECG. Recognizing Wellens' Syndrome, the ED physician had the patient transferred directly to the cath lab for immediate PCI.

Key points highlighted by this case:

  • Obtain Serial ECG's!
  • A single ECG diagnostic for STEMI is indication for cath lab activation.
  • Resolution of chest pain is not a reason to withold aspirin.
  • Wellens' Sydrome strongly suggests an advanced degree of LAD stenosis and requires urgent evaluation.

References

  • Dr. Smith's ECG Blog – Wellens' Syndrome
  • de Zwann C, Bar FW, Wellens HJJ. Characteristic electrocardiographic pattern indicating a critical stenosis high in left anterior descending coronary artery in patients admitted because of impending myocardial infarction. Am Heart J 1982; 103:730-736. [PubMed]
  • Parikh KS, Agarwal R, Mehrota AK, Swamy RS. Wellens syndrome: a life-saving diagnosis. Am J Emerg Med 2012; 30:255e3-255e5. [PubMed]
  • Rhinehardt J, Brady WJ, Perron AD, Mattu A. Electrocardiographic manifestations of Wellens' syndrome. Am J Emerg Med 2002; 20(7):638-43. [PubMed]

63 year old male CC: Syncope – Conclusion

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Here is the conlcusion to 63 year old male CC: Syncope.

First, let’s take another look at the 12-lead ECG.

This 12-lead ECG shows poor data quality.

This is a problem because the ECG is abnormal and suspicious for acute anterior STEMI.

We need to consider whether or not this could be benign early repolarization or a strain pattern from left ventricular hypertrophy.

This ECG does not meet the voltage criteria for LVH and does not have the general appearance of a “strain pattern” (but it would be nice to be able to take a nuanced look at the ST-segments and T-waves in leads I and aVL).

Could it be benign early repolarization?

Stephen Smith MD from Dr. Smith’s ECG Blog has come up with two different decision rules to help distinguish acute anterior STEMI from benign early repolarization.

Here they are in Dr. Smith’s own words:

Decision rule #1

If the mean R-wave amplitude from V2-V4 is less than 5 mm, then it is almost certainly MI. If greater than 5 mm, it is probably BER. A cutoff of 5 mm gives a sensitivity for MI of about 70%, but a specificity of greater than 95%.

In this case the first decision rule favors BER.

Decision rule #2

If 2 of the following 3 questions are answered “yes”, then it is MI with an accuracy of about 85%: 1) is the QTc > 392 ms? 2) Is the ST elevation at 60 ms after the J-point in lead V4 > 2mm? 3) Is the R-wave in V4 < 13 mm?

In this case the second decision rule favors acute anterior STEMI.

Do you see why this is such a difficult case?

I’ve said it before and I’ll say it again.

Sometimes the “go or no go” decision for the cardiac cath lab comes down to fractions of millimeters!

I really liked the way Tim Phalen explained the importance of serial 12-lead ECGs when we appeared together on the MedicCast at EMS Today 2010. He compared it to taking a single photograph of Old Faithful.

“Maybe it’s a geyser. Maybe it’s a hole in the ground.”

In this case a single 12-lead ECG was captured by the EMS crew. They did, however, obtain another rhythm strip as they were pulling into the hospital.

It appears as though this might show a change from the initial rhythm strip but we’re in monitor mode and a diagnostic quality 12-lead ECG should be used to observe changes on serial ECGs.

Let’s move on because poor data quality is about to rear its ugly head again. This time inside the hospital.

Here is the 12-lead ECG captured on arrival at the hospital.

Now we have a 12-lead ECG with excellent data quality.

When the medical chart was pulled it was discovered that the patient had a history of “remote inferior wall myocardial infarction”.

It was the next ECG that led to the patient becoming a “Code STEMI”.

You will note that someone has drawn brackets around the ST-segments in leads II and III.

This problem is, this isn’t ST-depression. This is artifact.

The ST-depression is not present in the first cardiac cycle. In addition, the baseline is shifted upwardly prior to the P-wave, marking this as some kind of wandering baseline or loose lead artifact.

Poor data quality continues in the right precordial leads.

From the cath report:

“The initial ECG in the emergency department was of concern because of ST-elevation in the anterior septal leads. This was not clear-cut acute myocardial injury-type ST-elevation. A follow-up ECG revealed the same findings and also non-specific inferior T-wave changes, possibly representing reciprocal changes. These changes were different in comparison with the previous ECG from our office in 2004. Therefore, ER physician’s consultation with me, we elected to treat this as a Code STEMI event.”

The patient was sent to the cardiac cath lab where angiography revealed no acute lesions.

Serial cardiac biomarkers came back negative.

The patient ruled out for acute myocardial infarction.

Please don’t think that I believe I’m perfect. I know that I’m not. All human beings make mistakes and that’s why patient safety experts like Peter Pronovost advocate designing systems that help minimize the impact of human error.

The first 12-lead ECG captured in the emergency department might have been reason enough to cath this patient (I am not in possession of the 12-lead ECG from 2004 so it’s difficult to speculate).

I also know that emergency physicians are under tremendous pressure not to delay care for acute STEMI patients.

It is impossible to identify acute STEMI with perfect sensitivity and specificity.

Having said that, poor data quality should not enter into the equation.

76 yom CC: Shortness of breath while walking

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Here is the story.

Patient is a 76 year old male. No known medical history, no meds, excellent physical condition, walks every day.

Two days prior the patient experienced some shortness of breath while walking, but the sensation went away with rest. Approximately 30 minutes prior to EMS arrival, patient walked outside to get the newspaper, bent down, and experienced some mild chest discomfort. The patient walked back inside and felt like someone was "standing on his chest." At this time the patient's spouse called 9-1-1.

At the time of EMS arrival, the patient appears acutely ill. He is slightly diaphoretic but not overly anxious. He admits to 8/10 chest pain and mild dyspnea. He denies nausea, vomiting, or palpitations. No JVD. Breath sounds are clear bilaterally.

Vital signs are assessed:

RR: 18
Pulse: 58
BP: 155/90
SpO2: 98 on RA

The cardiac monitor is attached.

A 12 lead ECG is captured.

What now?

Let us assume for the sake of discussion that you live in a rural community.

You are 25 minutes away from your local receiving hospital (no cath lab) and 55 minutes away from a hospital in the next county over that is capable of primary PCI.

Do you bypass the local community hospital?

Should the cardiac cath lab be activated prior to your arrival?

Who makes the decision?

41 year old male CC: Chest pain

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41 year old male complaining of chest discomfort.

The patient has had similar episodes before (after exertion), but in the past it always cleared up after use of an asthma inhaler.

EMS finds the patient sitting in a chair.

He had just taken a shower, with no relief of the chest discomfort.

He describes the pain as "heavy" and "unrelenting".

Skin cool, pale, and diaphoretic. Breath sounds clear bilaterally.

Past medical history: Asthma
Medications: Inhaler (unknown type)

Vital signs:

RR: 20
Pulse: 60
BP: 112/84
SpO2: 91 on RA

The cardiac monitor is attached.

A 12 lead ECG is captured.

What's going on here?

 

*** UPDATE ***

This following ECG was captured en route to the hospital. 

Look very carefully at lead V3!

Does this help with the diagnosis?

This case was especially difficult because our normal "tricks" to differentiate between acute anterior STEMI and benign early repolarization lead us in the wrong direction! 

In other words, R-wave progression is intact and the QTc is not prolonged.

In this case it's the serial ECGs that save the day.

Remember, there is no "always" in medicine!